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ABSTRACT
TITLE OF THE THESIS- SERUM AND SALIVARY URIC ACID LEVEL ESTIMATION AND ITS CORRELATION IN PREECLAMPSIA
BY-DR.SANGEETA PRADHAN
GUIDE-DR. PUSPAWATI THAKUR
The study was conducted in department of obstetrics and gynaecology,AIIMS RAIPUR from JUNE 2020 TO APRIL 2021.100 Antenatal women attending Obstetrics and Gynecology Antenatal OPD or admitted in Antenatal ward from 20-40 weeks of gestation fulfilling inclusion criteria (Inclusion criteria-Diagnostic Criteria for preeclampsia and severe preeclampsia As per Hypertension in pregnancy: diagnosis and management Nice guideline June 2019) and exclusion criteria were taken for study and divided into 2 groups.
Group I – It includes 50 Pregnant patients between 20 weeks – 4Oweeks of gestation diagnosed cases as preeclamps attending the Obstetrics and Gynaecology Outpatient department or admitted in Ante natal ward AIIMS, Raipur fulfilling inclusion and exclusion criteria.
GroupII –It includes 50 pregnant women between 20-40 weeks of gestation with normotensive pregnancy attending Obstetrics and Gynecology Antenatal OPD or admitted in Antenatal ward fulfilling inclusion and exclusion criteria.
The salivary sample and serum was sent to biochemistry labrotory and the findings were noted. There was linear correlation found between the salivary sample and serum uric sample values thus coming to the conclusion that elevated level of salivary uric acid precede the onset of preeclampsia, pregnancy-induced hypertension. uric acid may prove to be early biomarker of hypertensive complications of pregnancy .Serum uric acid can be used where routinely renal function tests cannot be done in low resource countries and developing countries like India.
